After Desmond Jennings' home run put the Rays up 5-0 in the fifth, the Twins responded with two in the top of the sixth, when Ryan Doumit singled home two runs. The play knocked Jeff Niemann out of the game, as his day ended after 5.1 innings allowing three hits, two walks and striking out five.
The Rays bullpen would shut down the Twins the rest of the way, while another sac fly by B.J. Upton in the bottom of the eighth gave Tampa Bay insurance.
Although he didn't knock any runs, Evan Longoria had a good game for the Rays, going 2-for-3 with a walk and run scored.
The Rays will now begin a series at home with the Los Angeles Angels of Anaheim on Tuesday.