The Jacksonville Jaguars host the Indianapolis Colts in Week 10's Thursday Night Football contest. The Colts were the source of Jacksonville's lone win of the season, a 22-17 victory in Week 3. Since then, the Jaguars have lost five in a row, while the Colts have won four of five.

Maurice Jones-Drew contributed 177 yards and a touchdown in their previous victory, but the Jags will be without him on Sunday. His foot injury will keep him sidelined for his third straight game. That leaves the offense in the hands of Blaine Gabbert, who had a season-high 71.1 completion percentage and two touchdowns against the Lions. He also had two interceptions as the Jaguars fell, 31-14. Jacksonville ranks last in the league in total offense, with 254 yards per game.

The defense has its share of the blame. They're last in the league in sacks, third from the bottom in interceptions, and rank 25th in total yards allowed.

Even aside from the earlier win, recent history is on Jacksonville's side. Gabbert is 3-0 against the Colts. He'll try to lead Jacksonville out of the cellar on Sunday in search of his fourth straight.

The game begins at 8:20 p.m. ET, with television coverage provided by the NFL Network.