The Jaguars will be without offensive lineman Uche Nwaneri, who hasn't been able to practice this week because of a concussion. Nwaneri started the first 15 games of the season for Jacksonville and has been a regular up front for the Jaguars since the 2008 season.
Defensive tackle Tyson Alualu (calf), fullback Greg Jones (thigh), cornerback Rashean Mathis (groin), center Brad Meester (foot), linebacker Paul Posluszny (groin), cornerback Aaron Ross (calf), linebacker Daryl Smith (groin) and linebacker Julian Stanford (hip) are probable. Running back Maurice Jones-Drew is having surgery on his injured foot and is expected to be out of action until May.
The Titans could be without a significant number of players this weekend, including running back Chris Johnson, who is questionable with an ankle injury. Quarterback Jake Locker is probable despite a left shoulder injury. Safeties Jordan Babineaux (thigh) and Michael Griffin (illness) are also probable, as is wide receiver Kenny Britt (knee).
Center Kevin Matthews (ankle), linebacker Colin McCarthy (concussion) and tight end Craig Stevens (concussion) are out. Running back Jamie Harper (ankle), wide receiver Kendall Wright (rib), linebacker Will Witherspoon (chest), wide receiver Damian Williams (foot), defensive end Scott Solomon (knee) and cornerback Ryan Mouton (hamstring) are questionable.