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South Florida vs. Cincinnati: One of just two night games on Friday, the season for South Florida will mercifully come to an end against the Bearcats. Although the season started with five straight wins for Cincinnati, the team has won just two of its last five. The Bulls have lost seven of their last eight, though. Friday, 7 p.m. ET, ESPN
UAB vs. UCF: The Knights are one more win away from securing the Conference-USA's East Division. The only team standing in its way is the Blazers, a team that was blown out by Memphis last weekend. Saturday, 12 p.m. ET, FOX Sports Regional
Miami (Fla.) vs. Duke: Both Miami and Duke are bowl eligible, but right in the middle of the ACC standings. If the Hurricanes can manage a win, they have a chance to still win the ACC's Coastal Division, but the team will first have to give Duke its fourth consecutive loss. Saturday, 1 p.m. ET, ACC Network/ESPN 3
Coastal Carolina vs. Bethune-Cookman: The playoffs begin for the Bethune-Cookman Wildcats on Saturday as the team will look for an eighth consecutive victory. The Chanticleers are on a hot streak as well, though, and have won five in a row entering the first-round game. Saturday, 2 p.m. ET
Florida vs. Florida State: The annual game between the Gators and Seminoles always has intrigue, but not often do the two teams meet with both ranked in the BCS top 10. The Gators are still clinging to hope for a BCS National Championship Game, but the Noles can ruin that and secure themselves a top BCS Bowl with a victory. Saturday, 3:30 p.m. ET, ABC
Louisiana-Monroe vs. Florida International: The season will end on Saturday for FIU, as it cannot reach blow-eligibility even with a victory. A promising season for the WarHawks turned sour recently with back-to-back losses, but with a win against the Golden Panthers, ULM could still get a selection to a respectable bowl game. Saturday, 6 p.m. ET