LSU vs. Florida 2012: TV schedule, game time, spread and more

No. 10 Florida hosts No. 4 LSU in one of the weekend's biggest college football games. LSU slipped in the rankings after a mixed effort against Towson, and Florida's string of victories has eyeing the game as the week's best chance for an upset.

LSU quarterback Zach Mettenberger struggled on the road against Auburn, going 15-for-27 for 169 yards while fumbling twice. Gator fans hope that he mirrors that performance in The Swamp, where he'll face a defense giving up an average of 12.8 points per game, good for 10th in the FBS.

Les Miles has a colorful history vs. Florida, and a 1-2 record when playing Florida on the road. Florida senior running back Mike Gillislee hopes to make it 1-3 by pushing the Gators' rushing attack, currently averaging 225 yards per game. That will be no small feat against the LSU defense, who is ranked just above Florida at No. 9, with an average of 12.6 points allowed per game.

Game Time: 3:30 p.m. ET
Television Coverage: CBS
Odds: LSU favored by 2.5 points