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South Florida vs. Louisville 2012 odds: Cardinals a 6.5-point favorite over Bulls

The No. 16 Louisville Cardinals are a 6.5-point favorite this weekend against the South Florida Bulls.

Al Messerschmidt - Getty Images

The No. 16 Louisville Cardinals are nearly a touchdown favorite this week against the South Florida Bulls. According to OddShark, the Cardinals opened as a nine-point favorite, but that number has since come down to 6.5 points. The total for the game opened at 52.5 points, but it has moved up slightly in the past couple of days.

Louisville (6-0) is coming off a 45-35 victory at Pittsburgh last week. Prior to that, the Cardinals had won their last three games by a combined 16 points. For the season, the Cardinals have gone 3-3 against the spread.

South Florida (2-4) is riding a four-game losing streak into this weekend's action, and the Bulls have gone just 1-7-1 against the spread in their last nine games dating back to last season. That lone cover came on Sept. 29 of this season when the Bulls competed surprisingly well against the Florida State Seminoles.

Louisville won last season's matchup 34-24.

Photographs by cstreet.us, thelastminute, turtlemom nancy , fesek, kthypryn, justinwright, sue_elias, pointnshoot, and scrapstothefuture used in background montage under Creative Commons. Thank you.